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Readers of histone modifications.


ABSTRACT: Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as epigenetic marks. Accumulating evidence suggests that the key function of histone modifications is to signal for recruitment or activity of downstream effectors. Here, we discuss the latest discovery of histone-modification readers and how the modification language is interpreted.

SUBMITTER: Yun M 

PROVIDER: S-EPMC3131977 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature

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Readers of histone modifications.

Yun Miyong M   Wu Jun J   Workman Jerry L JL   Li Bing B  

Cell research 20110322 4


Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as epigenetic marks. Accumulating evidence suggests that the key function of histone modifications is to signal for recruitment or activity of downstream effectors. Here, we discuss the latest discovery of histone-modification readers and how the modification language is interpreted. ...[more]

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