Genome-wide identification of transcription start sites yields a novel thermosensing RNA and new cyclic AMP receptor protein-regulated genes in Escherichia coli.
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ABSTRACT:
SUBMITTER: Raghavan R
PROVIDER: S-EPMC3133129 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
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Genome-wide identification of transcription start sites yields a novel thermosensing RNA and new cyclic AMP receptor protein-regulated genes in Escherichia coli.
Raghavan Rahul R Sage Alan A Ochman Howard H
Journal of bacteriology 20110401 11
Intergenic regions often contain regulatory elements that control the expression of flanking genes. Using a deep-sequencing approach, we identified numerous new transcription start sites in Escherichia coli, yielding a new thermosensing regulatory RNA and seven genes previously unknown to be under the control of the global regulator CRP. ...[more]
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