Ontology highlight
ABSTRACT:
SUBMITTER: Gutierrez-Escribano P
PROVIDER: S-EPMC3135472 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Gutiérrez-Escribano Pilar P González-Novo Alberto A Suárez M Belén MB Li Chang-Run CR Wang Yue Y de Aldana Carlos R Vázquez CR Correa-Bordes Jaime J
Molecular biology of the cell 20110518 14
Nuclear Dbf2-related (NDR) protein kinases are essential components of regulatory pathways involved in cell morphogenesis, cell cycle control, and viability in eukaryotic cells. For their activity and function, these kinases require interaction with Mob proteins. However, little is known about how the Mob proteins are regulated. In Candida albicans, the cyclin-dependent kinase (CDK) Cdc28 and the NDR kinase Cbk1 are required for hyphal growth. Here we demonstrate that Mob2, the Cbk1 activator, u ...[more]