Ontology highlight
ABSTRACT:
SUBMITTER: Jezewski PA
PROVIDER: S-EPMC3140304 | biostudies-literature | 2008 Sep
REPOSITORIES: biostudies-literature
Jezewski Peter A PA Fang Ping-Ke PK Payne-Ferreira Tracie L TL Yelick Pamela Crotty PC
Zebrafish 20080901 3
Roles for Wnt9b in craniofacial development are indicated by the cleft lip mutant phenotype observed in the A/WySn mouse strain,(1) caused by a retrotransposon insertion mutation at the Wnt9b locus. Analyses of the zebrafish Wnt9b ortholog, wnt9b, were pursued to provide insight into early vertebrate craniofacial patterning events mediated by Wnt9b signaling. Zebrafish wnt9b cDNA clones were isolated and found to encode an open reading frame of 358 amino acids, with 68% amino acid identity to mo ...[more]