Ontology highlight
ABSTRACT:
SUBMITTER: Jackson JR
PROVIDER: S-EPMC3143346 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Jackson Janna R JR Ryan Michael J MJ Alway Stephen E SE
The journals of gerontology. Series A, Biological sciences and medical sciences 20110331 7
This study analyzed the capacity of resveratrol, a naturally occurring polyphenol, to reduce aging-induced oxidative stress and protect against sarcopenia. Middle-aged (18 months) C57/BL6 mice were randomly assigned to receive either a control diet or a diet supplemented with 0.05% trans-resveratrol for 10 months. Young (6 months) and middle-aged (18 months) mice were used as controls. Resveratrol supplementation did not reduce the aging-associated loss of muscle mass or improve maximal isometri ...[more]