Ontology highlight
ABSTRACT:
SUBMITTER: Ebrahimi KB
PROVIDER: S-EPMC3147126 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Ebrahimi Katayoon B KB Handa James T JT
Journal of lipids 20110728
Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly. While excellent treatment has emerged for neovascular disease, treatment for early AMD is lacking due to an incomplete understanding of the early molecular events. A prominent age-related change is the accumulation of neutral lipid in normal Bruch's membrane (BrM) throughout adulthood and also disease-related BrM accumulations called basal deposits and drusen. AMD lesion formation has thus been conceptual ...[more]