New diagnostic microarray (Check-KPC ESBL) for detection and identification of extended-spectrum beta-lactamases in highly resistant Enterobacteriaceae.
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ABSTRACT:
SUBMITTER: Willemsen I
PROVIDER: S-EPMC3147782 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
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New diagnostic microarray (Check-KPC ESBL) for detection and identification of extended-spectrum beta-lactamases in highly resistant Enterobacteriaceae.
Willemsen Ina I Overdevest Ilse I Al Naiemi Nashwan N Rijnsburger Martine M Savelkoul Paul P Vandenbroucke-Grauls Christina C Kluytmans Jan J
Journal of clinical microbiology 20110608 8
The performance of a microarray for the detection of extended-spectrum beta-lactamases was determined on a collection of 638 highly resistant members of the family Enterobacteriaceae collected from patients in 18 hospitals in The Netherlands. The microarray had a significantly higher specificity than the phenotypic assays. It also detects carbapenemases and characterizes the resistance genes, providing epidemiological insight. ...[more]
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