Ontology highlight
ABSTRACT:
SUBMITTER: Stein C
PROVIDER: S-EPMC3818264 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Stein Claudia C Makarewicz Oliwia O Pfeifer Yvonne Y Brandt Christian C Ramos João Costa JC Klinger Mareike M Pletz Mathias W MW
PloS one 20131105 11
The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with subsequently increased mortality. From a clinical perspective, fast detection of resistant pathogens would allow a pre-emptive correction of an initially inappropriate treatment. Here we present diagnostic amplification-sequencing approach as proof of principal based on the fast mo ...[more]