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Identification of the first human gyrovirus, a virus related to chicken anemia virus.

ABSTRACT: We have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously known member of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesional skin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspirates and in 0 of 92 fecal samples.

SUBMITTER: Sauvage V

PROVIDER: S-EPMC3147908 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature

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Identification of the first human gyrovirus, a virus related to chicken anemia virus.

Sauvage Virginie V Cheval Justine J Foulongne Vincent V Gouilh Meriadeg Ar MA Pariente Kevin K Manuguerra Jean Claude JC Richardson Jennifer J Dereure Olivier O Lecuit Marc M Burguiere Ana A Caro Valérie V Eloit Marc M

Journal of virology 20110601 15

We have identified in a skin swab sample from a healthy donor a new virus that we have named human gyrovirus (HGyV) because of its similarity to the chicken anemia virus (CAV), the only previously known member of the Gyrovirus genus. In particular, this virus encodes a homolog of the CAV apoptin, a protein that selectively induces apoptosis in cancer cells. By PCR screening, HGyV was found in 5 of 115 other nonlesional skin specimens but in 0 of 92 bronchoalveolar lavages or nasopharyngeal aspir ...[more]

PMID: 21632766

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Genetic Analysis of Two Chicken Infectious Anemia Virus Variants-Related <i>Gyrovirus</i> in Stray Mice and Dogs: The First Report in China, 2015.

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First detection and genetic characterization of chicken infectious anemia virus in the Mekong Delta, Vietnam.

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Molecular characterization and the first full sequencing genome of chicken infectious anemia virus (CIAV) in Iran.

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| S-EPMC8806177 | biostudies-literature

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