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Assessment of dyspnea in asthma: validation of The Dyspnea-12.


ABSTRACT: Dyspnea is a prominent symptom in asthma. The Dyspnea-12 (D-12), an instrument that quantifies breathlessness using 12 descriptors that tap the physical and affective aspects, has shown promise for the measurement of dyspnea in cardiorespiratory disease.We report the results of a study designed to test the validity and reliability of the D-12 in a population of patients with asthma.This cross-sectional study included 102 patients with asthma. Subjects completed the D-12, Hospital Anxiety and Depression scale, St. George's Respiratory Questionnaire (SGRQ), and Medical Research Council scale. Confirmatory factor analysis confirmed the two-component structure of the D-12 (i.e., seven items that tap the physical aspects of breathlessness and five items that tap the affective aspects).The D-12 subscales had excellent internal reliability (Cronbach's alpha for the "physical" score was 0.94 and the affective score was 0.95). The D-12 physical component was more strongly correlated with SGRQ Symptoms (r = 0.648), SGRQ Activities (r = 0.635) and Medical Research Council grade (r = 0.636), while the affective component was more strongly correlated with SGRQ Impacts (r = 0.765) and Hospital Anxiety and Depression scale scores (anxiety r = 0.641 and depression r = 0.602).This study supports validity of the D-12 for use in the assessment of dyspnea of patients with asthma. It assesses one of the most pertinent symptoms of asthma from two viewpoints-physical and affective.

SUBMITTER: Yorke J 

PROVIDER: S-EPMC3149863 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature

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Assessment of dyspnea in asthma: validation of The Dyspnea-12.

Yorke Janelle J   Russell Anne-Marie AM   Swigris Jeff J   Shuldham Caroline C   Haigh Carol C   Rochnia Nikki N   Hoyle Jennifer J   Jones Paul W PW  

The Journal of asthma : official journal of the Association for the Care of Asthma 20110602 6


<h4>Background</h4>Dyspnea is a prominent symptom in asthma. The Dyspnea-12 (D-12), an instrument that quantifies breathlessness using 12 descriptors that tap the physical and affective aspects, has shown promise for the measurement of dyspnea in cardiorespiratory disease.<h4>Objective</h4>We report the results of a study designed to test the validity and reliability of the D-12 in a population of patients with asthma.<h4>Methods</h4>This cross-sectional study included 102 patients with asthma.  ...[more]

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