Ontology highlight
ABSTRACT:
SUBMITTER: Diester I
PROVIDER: S-EPMC3150193 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Diester Ilka I Kaufman Matthew T MT Mogri Murtaza M Pashaie Ramin R Goo Werapong W Yizhar Ofer O Ramakrishnan Charu C Deisseroth Karl K Shenoy Krishna V KV
Nature neuroscience 20110130 3
Optogenetics is a technique for controlling subpopulations of neurons in the intact brain using light. This technique has the potential to enhance basic systems neuroscience research and to inform the mechanisms and treatment of brain injury and disease. Before launching large-scale primate studies, the method needs to be further characterized and adapted for use in the primate brain. We assessed the safety and efficiency of two viral vector systems (lentivirus and adeno-associated virus), two h ...[more]