Ontology highlight
ABSTRACT:
SUBMITTER: Antinucci P
PROVIDER: S-EPMC7170653 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Antinucci Paride P Dumitrescu Adna A Deleuze Charlotte C Morley Holly J HJ Leung Kristie K Hagley Tom T Kubo Fumi F Baier Herwig H Bianco Isaac H IH Wyart Claire C
eLife 20200327
Optogenetic actuators with diverse spectral tuning, ion selectivity and kinetics are constantly being engineered providing powerful tools for controlling neural activity with subcellular resolution and millisecond precision. Achieving reliable and interpretable in vivo optogenetic manipulations requires reproducible actuator expression and calibration of photocurrents in target neurons. Here, we developed nine transgenic zebrafish lines for stable opsin expression and calibrated their efficacy i ...[more]