Ontology highlight
ABSTRACT:
SUBMITTER: Barbalic M
PROVIDER: S-EPMC3150445 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Barbalic Maja M Reiner Alex P AP Wu Chunyuan C Hixson James E JE Franceschini Nora N Eaton Charles B CB Heiss Gerardo G Couper David D Mosley Thomas T Boerwinkle Eric E
PLoS genetics 20110804 8
African Americans have the highest rate of mortality due to coronary heart disease (CHD). Although multiple loci have been identified influencing CHD risk in European-Americans using a genome-wide association (GWAS) approach, no GWAS of incident CHD has been reported for African Americans. We performed a GWAS for incident CHD events collected during 19 years of follow-up in 2,905 African Americans from the Atherosclerosis Risk in Communities (ARIC) study. We identified a genome-wide significant ...[more]