Ontology highlight
ABSTRACT:
SUBMITTER: Keskitalo-Vuokko K
PROVIDER: S-EPMC3150688 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Keskitalo-Vuokko Kaisu K Pitkäniemi Janne J Broms Ulla U Heliövaara Markku M Aromaa Arpo A Perola Markus M Ripatti Samuli S Salminen Outi O Salomaa Veikko V Loukola Anu A Kaprio Jaakko J
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110416 8
<h4>Introduction</h4>Genetic effects contribute to individual differences in smoking behavior. Persistence to smoke despite known harmful health effects is mostly driven by nicotine addiction. As the physiological effects of nicotine are mediated by nicotinic acetylcholine receptors (nAChRs), we aimed at examining whether single nucleotide polymorphisms (SNPs) residing in nAChR subunit (CHRN) genes, other than CHRNA3/CHRNA5/CHRNB4 gene cluster previously showing association in our sample, are as ...[more]