Ontology highlight
ABSTRACT:
SUBMITTER: Taylor KC
PROVIDER: S-EPMC3153310 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Taylor Kira C KC Lange Leslie A LA Zabaneh Delilah D Lange Ethan E Keating Brendan J BJ Tang Weihong W Smith Nicholas L NL Delaney Joseph A JA Kumari Meena M Hingorani Aroon A North Kari E KE Kivimaki Mika M Tracy Russell P RP O'Donnell Christopher J CJ Folsom Aaron R AR Green David D Humphries Steve E SE Reiner Alexander P AP
Human molecular genetics 20110615 17
Polymorphisms in several distinct genomic regions, including the F7 gene, were recently associated with factor VII (FVII) levels in European Americans (EAs). The genetic determinants of FVII in African Americans (AAs) are unknown. We used a 50,000 single nucleotide polymorphism (SNP) gene-centric array having dense coverage of over 2,000 candidate genes for cardiovascular disease (CVD) pathways in a community-based sample of 16,324 EA and 3898 AA participants from the Candidate Gene Association ...[more]