Ontology highlight
ABSTRACT:
SUBMITTER: Wassel CL
PROVIDER: S-EPMC3037748 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Wassel Christina L CL Lange Leslie A LA Keating Brendan J BJ Taylor Kira C KC Johnson Andrew D AD Palmer Cameron C Ho Lindsey A LA Smith Nicholas L NL Lange Ethan M EM Li Yun Y Yang Qiong Q Delaney Joseph A JA Tang Weihong W Tofler Geoffrey G Redline Susan S Taylor Herman A HA Wilson James G JG Tracy Russell P RP Jacobs David R DR Folsom Aaron R AR Green David D O'Donnell Christopher J CJ Reiner Alexander P AP
Blood 20101026 1
Several common genomic loci, involving various immunity- and metabolism-related genes, have been associated with plasma fibrinogen in European Americans (EAs). The genetic determinants of fibrinogen in African Americans (AAs) are poorly characterized. Using a vascular gene-centric array in 23,634 EA and 6657 AA participants from 6 studies comprising the Candidate Gene Association Resource project, we examined the association of 47,539 common and lower frequency variants with fibrinogen concentra ...[more]