Ontology highlight
ABSTRACT:
SUBMITTER: Martinez HP
PROVIDER: S-EPMC3155153 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Martinez H Paul HP Kono Yuko Y Blair Sarah L SL Sandoval Sergio S Wang-Rodriguez Jessica J Mattrey Robert F RF Kummel Andrew C AC Trogler William C WC
MedChemComm 20101001 4
Hollow hard shell particles of 200 nm and 2 micron diameter with a 10 nm thick porous silica shell have been synthesized using polystyrene templates and a sol-gel process. The template ensures than the hollow particles are monodispersed, while the charged silica surface ensures that they remain suspended in solution for weeks. When filled with perfluorocarbon gas, the particles behave as an efficient contrast agent for colour Doppler ultrasound imaging in human breast tissue. The silica shell pr ...[more]