Gas-generating nanoparticles for contrast-enhanced ultrasound imaging.
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ABSTRACT:
SUBMITTER: Sun IC
PROVIDER: S-EPMC6759366 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Gas-generating nanoparticles for contrast-enhanced ultrasound imaging.
Sun In-Cheol IC Emelianov Stanislav S
Nanoscale 20190827 35
We present gas-generating solid nanoparticles as a new concept of an ultrasound contrast agent. The developed nanoparticles are sufficiently small (less than 100 nm in diameter) to escape vasculature and yet, upon external pulsed laser light activation, release nitrogen gas for enhanced contrast in ultrasound imaging. The gas-generating nanoconstructs combine the photocatalytic function of gold nanoparticles and photolysis of azide compounds. Using ultrasound imaging, we demonstrate the controll ...[more]
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