Ontology highlight
ABSTRACT:
SUBMITTER: Li Q
PROVIDER: S-EPMC3155975 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Li Qiyuan Q Eklund Aron C AC Birkbak Nicolai J NJ Desmedt Christine C Haibe-Kains Benjamin B Sotiriou Christos C Symmans W Fraser WF Pusztai Lajos L Brunak Søren S Richardson Andrea L AL Szallasi Zoltan Z
BMC bioinformatics 20110728
<h4>Background</h4>Genome scale expression profiling of human tumor samples is likely to yield improved cancer treatment decisions. However, identification of clinically predictive or prognostic classifiers can be challenging when a large number of genes are measured in a small number of tumors.<h4>Results</h4>We describe an unsupervised method to extract robust, consistent metagenes from multiple analogous data sets. We applied this method to expression profiles from five "double negative breas ...[more]