Ontology highlight
ABSTRACT:
SUBMITTER: Guevorkian K
PROVIDER: S-EPMC3158194 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Guevorkian Karine K Gonzalez-Rodriguez David D Carlier Camille C Dufour Sylvie S Brochard-Wyart Françoise F
Proceedings of the National Academy of Sciences of the United States of America 20110715 33
During embryonic development and wound healing, the mechanical signals transmitted from cells to their neighbors induce tissue rearrangement and directional movements. It has been observed that forces exerted between cells in a developing tissue under stress are not always monotonically varying, but they can be pulsatile. Here we investigate the response of model tissues to controlled external stresses. Spherical cellular aggregates are subjected to one-dimensional stretching forces using microp ...[more]