Ontology highlight
ABSTRACT:
SUBMITTER: Gardner AF
PROVIDER: S-EPMC3158340 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Gardner Andrew F AF Prangishvili David D Jack William E WE
Extremophiles : life under extreme conditions 20110611 5
The hyperthermophilic Sulfolobus islandicus rod-shaped virus 2 (SIRV2) encodes a 25-kDa protein (SIRV2gp19) annotated as a hypothetical protein with sequence homology to the RecB nuclease superfamily. Even though SIRV2gp19 homologs are conserved throughout the rudivirus family and presumably play a role in the viral life cycle, SIRV2gp19 has not been functionally characterized. To define the minimal requirements for activity, SIRV2gp19 was purified and tested under varying conditions. SIRV2gp19 ...[more]