Ontology highlight
ABSTRACT:
SUBMITTER: Cho BK
PROVIDER: S-EPMC3159470 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Nucleic acids research 20110513 15
The PurR transcription factor plays a critical role in transcriptional regulation of purine metabolism in enterobacteria. Here, we elucidate the role of PurR under exogenous adenine stimulation at the genome-scale using high-resolution chromatin immunoprecipitation (ChIP)-chip and gene expression data obtained under in vivo conditions. Analysis of microarray data revealed that adenine stimulation led to changes in transcript level of about 10% of Escherichia coli genes, including the purine bios ...[more]