Ontology highlight
ABSTRACT:
SUBMITTER: Moore E
PROVIDER: S-EPMC3159901 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Annals of intensive care 20110321 1
Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is mostly well-known for its physiological function in regulating red blood cell production in the bone marrow. Accumulating evidence, however, suggests that EPO has additional organ protective effects, which may be useful in the prevention or treatment of acute kidney injury. These protective mechanisms are multifactorial in nature and include inhibition of apoptotic cell death, stimulation of cellular regeneration, inh ...[more]