Ontology highlight
ABSTRACT:
SUBMITTER: Wagner R
PROVIDER: S-EPMC3161735 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20110822 8
<h4>Introduction</h4>Recent meta-analyses of genome-wide association studies revealed new genetic loci associated with fasting glycemia. For several of these loci, the mechanism of action in glucose homeostasis is unclear. The objective of the study was to establish metabolic phenotypes for these genetic variants to deliver clues to their pathomechanism.<h4>Methods</h4>In this cross-sectional study 1782 non-diabetic volunteers at increased risk for type 2 diabetes underwent an oral glucose toler ...[more]