Ontology highlight
ABSTRACT:
SUBMITTER: Leong HS
PROVIDER: S-EPMC3163450 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Leong Hon Sing HS Steinmetz Nicole F NF Ablack Amber A Destito Giuseppe G Zijlstra Andries A Stuhlmann Heidi H Manchester Marianne M Lewis John D JD
Nature protocols 20100708 8
Viral nanoparticles are a novel class of biomolecular agents that take advantage of the natural circulatory and targeting properties of viruses to allow the development of therapeutics, vaccines and imaging tools. We have developed a multivalent nanoparticle platform based on the cowpea mosaic virus (CPMV) that facilitates particle labeling at high density with fluorescent dyes and other functional groups. Compared with other technologies, CPMV-based viral nanoparticles are particularly suited f ...[more]