Ontology highlight
ABSTRACT:
SUBMITTER: Cho CF
PROVIDER: S-EPMC5770569 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Cho Choi-Fong CF Yu Lihai L Nsiama Tienabe K TK Kadam Alisha N AN Raturi Arun A Shukla Sourabh S Amadei Giulio A GA Steinmetz Nicole F NF Luyt Leonard G LG Lewis John D JD
Nanoscale 20170801 33
Angiogenesis is a dynamic process fundamental to the development of solid tumors. Epidermal growth factor-like domain 7 (EGFL7) is a protein whose expression is restricted to endothelial cells undergoing active remodeling that has emerged as a key mediator of this process. EGFL7 expression is associated with poor outcome in several cancers, making it a promising target for imaging or therapeutic strategies. Here, EGFL7 is explored as a molecular target for active neovascularization. Using a comb ...[more]