Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC3164213 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20110810 35
Efficient access to chiral C(sp(3)) boronates in stereochemically pure form is critical for realizing the substantial potential of such building blocks in complex-molecule synthesis. We herein report that a pinene-derived iminodiacetic acid (PIDA) ligand enables the highly diastereoselective synthesis of a wide range of oxiranyl C(sp(3)) boronates from the corresponding olefins. These oxiranyl PIDA boronates, in turn, can be readily transformed into unprecedented stable α-boryl aldehydes via a n ...[more]