Ontology highlight
ABSTRACT:
SUBMITTER: Lamb AL
PROVIDER: S-EPMC3164438 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Biochemistry 20110812 35
One of the fundamental questions of enzymology is how catalytic power is derived. This review focuses on recent developments in the structure--function relationships of chorismate-utilizing enzymes involved in siderophore biosynthesis to provide insight into the biocatalysis of pericyclic reactions. Specifically, salicylate synthesis by the two-enzyme pathway in Pseudomonas aeruginosa is examined. The isochorismate-pyruvate lyase is discussed in the context of its homologues, the chorismate muta ...[more]