Ontology highlight
ABSTRACT:
SUBMITTER: Ricketts SL
PROVIDER: S-EPMC3166154 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Ricketts Sally L SL Rensing Katrijn L KL Holly Jeff M JM Chen Li L Young Elizabeth H EH Luben Robert R Ashford Sofie S Song Kijoung K Yuan Xin X Dehghan Abbas A Wright Benjamin J BJ Waterworth Dawn M DM Mooser Vincent V Waeber Gérard G Vollenweider Peter P Epstein Stephen E SE Burnett Mary S MS Devaney Joseph M JM Hakonarson Hakon H HH Rader Daniel J DJ Reilly Muredach P MP Danesh John J Thompson Simon G SG Dunning Alison M AM van Duijn Cornelia M CM Samani Nilesh J NJ McPherson Ruth R Wareham Nicholas J NJ Khaw Kay-Tee KT Boekholdt S Matthijs SM Sandhu Manjinder S MS
International journal of molecular epidemiology and genetics 20110803 3
Although experimental studies have suggested that insulin-like growth factor I (IGF-I) and its binding protein IGFBP-3 might have a role in the aetiology of coronary artery disease (CAD), the relevance of circulating IGFs and their binding proteins in the development of CAD in human populations is unclear. We conducted a nested case-control study, with a mean follow-up of six years, within the EPIC-Norfolk cohort to assess the association between circulating levels of IGF-I and IGFBP-3 and risk ...[more]