Ontology highlight
ABSTRACT:
SUBMITTER: Sun VZ
PROVIDER: S-EPMC3166235 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Sun Victor Z VZ Li Zhibo Z Deming Timothy J TJ Kamei Daniel T DT
Biomacromolecules 20101203 1
The block copolypeptide poly(l-homoarginine)(60)-b-poly(l-leucine)(20) (R(60)L(20)) was previously found to self-assemble into versatile vesicles with controllable size and encapsulate hydrophilic cargo. These R(60)L(20) vesicles also demonstrated the ability to cross the cell membrane and transport encapsulated cargo into different cell lines. To assess the potential for using the R(60)L(20) vesicles as drug delivery vehicles further, we have investigated their endocytosis and intracellular tra ...[more]