Ontology highlight
ABSTRACT:
SUBMITTER: Moisello C
PROVIDER: S-EPMC3167928 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Moisello Clara C Perfetti Bernardo B Marinelli Lucio L Sanguineti Vittorio V Bove Marco M Feigin Andrew A Di Rocco Alessandro A Eidelberg David D Ghilardi M F MF
Parkinsonism & related disorders 20110720 8
Movement kinematic variables related to force production can be modulated to respond appropriately to different contexts. We previously showed that in a choice-reaction time and a predictable timed-response task, normal subjects perform reaching movements to the same targets with two different kinematic patterns, a marker of flexibility. Here, we used the two tasks to determine whether basal ganglia are involved in the selection and modulation of movement kinematics and therefore in flexible for ...[more]