Ontology highlight
ABSTRACT:
SUBMITTER: Davies DR
PROVIDER: S-EPMC3169400 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Davies Douglas R DR Staker Bart L BL Abendroth Jan A JA Edwards Thomas E TE Hartley Robert R Leonard Jess J Kim Hidong H Rychel Amanda L AL Hewitt Stephen N SN Myler Peter J PJ Stewart Lance J LJ
Acta crystallographica. Section F, Structural biology and crystallization communications 20110813 Pt 9
Burkholderia pseudomallei is a soil-dwelling bacterium endemic to Southeast Asia and Northern Australia. Burkholderia is responsible for melioidosis, a serious infection of the skin. The enzyme 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (PGAM) catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate, a key step in the glycolytic pathway. As such it is an extensively studied enzyme and X-ray crystal structures of PGAM enzymes from multiple species have been elucid ...[more]