Ontology highlight
ABSTRACT:
SUBMITTER: Hyun JK
PROVIDER: S-EPMC3169552 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Hyun Jae-Kyung JK Accurso Cathy C Hijnen Marcel M Schult Philipp P Pettikiriarachchi Anne A Mitra Alok K AK Coulibaly Fasséli F
PLoS pathogens 20110908 9
In contrast to most enveloped viruses, poxviruses produce infectious particles that do not acquire their internal lipid membrane by budding through cellular compartments. Instead, poxvirus immature particles are generated from atypical crescent-shaped precursors whose architecture and composition remain contentious. Here we describe the 2.6 Å crystal structure of vaccinia virus D13, a key structural component of the outer scaffold of viral crescents. D13 folds into two jellyrolls decorated by a ...[more]