Ontology highlight
ABSTRACT:
SUBMITTER: Shaddox LM
PROVIDER: S-EPMC3169885 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Shaddox L M LM Wiedey J J Calderon N L NL Magnusson I I Bimstein E E Bidwell J A JA Zapert E F EF Aukhil I I Wallet S M SM
Journal of dental research 20110705 9
While much research has focused on local and systemic factors contributing to periodontal disease, little is known regarding mechanisms linking these factors. We have previously reported a systemic hyper-inflammatory response to bacterial endotoxin in localized aggressive periodontitis (LAP). The objectives of this study were to delineate cyto/chemokines in gingival crevicular fluid (GCF) and evaluate systemic levels of endotoxin associated with LAP. Clinical parameters, GCF, and peripheral bloo ...[more]