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ABSTRACT:
SUBMITTER: Struffi P
PROVIDER: S-EPMC3171227 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Struffi Paolo P Corado Maria M Kaplan Leah L Yu Danyang D Rushlow Christine C Small Stephen S
Development (Cambridge, England) 20110824 19
Despite years of study, the precise mechanisms that control position-specific gene expression during development are not understood. Here, we analyze an enhancer element from the even skipped (eve) gene, which activates and positions two stripes of expression (stripes 3 and 7) in blastoderm stage Drosophila embryos. Previous genetic studies showed that the JAK-STAT pathway is required for full activation of the enhancer, whereas the gap genes hunchback (hb) and knirps (kni) are required for plac ...[more]