Ontology highlight
ABSTRACT:
SUBMITTER: Huang RY
PROVIDER: S-EPMC3171746 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Huang Richard Y-C RY Laing James G JG Kanter Evelyn M EM Berthoud Viviana M VM Bao Mingwei M Rohrs Henry W HW Townsend R Reid RR Yamada Kathryn A KA
Journal of proteome research 20110204 3
Connexin43 (Cx43) is a major cardiac gap junction channel protein required for normal electrical and contractile activity. Gap junction channel assembly, function, and turnover are regulated by phosphorylation under both normal and disease conditions. The carboxyl terminus (CT) of Cx43 contains numerous amino acid residues that are phosphorylated by protein kinases. However, our knowledge of the specific residues and kinases involved is incomplete. The objective of this study was to identify ami ...[more]