Ontology highlight
ABSTRACT:
SUBMITTER: Gu J
PROVIDER: S-EPMC3172962 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Personalized medicine 20110501 3
Bladder cancer is an excellent model for studying genetic susceptibility and gene-environment interaction in cancer etiology. The candidate gene approach found NAT2 slow acetylator and GSTM1-null genotypes to be bladder cancer susceptibility loci and also demonstrated interactions between these two genotypes and smoking in modulating bladder cancer risk. Recent genome-wide association studies identified at least eight novel genetic susceptibility loci for bladder cancer. Genetic determinants of ...[more]