Fragmentation is crucial for the steady-state dynamics of actin filaments.
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ABSTRACT:
SUBMITTER: Schmoller KM
PROVIDER: S-EPMC3175074 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Fragmentation is crucial for the steady-state dynamics of actin filaments.
Schmoller Kurt M KM Niedermayer Thomas T Zensen Carla C Wurm Christine C Bausch Andreas R AR
Biophysical journal 20110801 4
Despite the recognition that actin filaments are important for numerous cellular processes, and decades of investigation, the dynamics of in vitro actin filaments are still not completely understood. Here, we follow the time evolution of the length distribution of labeled actin reporter filaments in an unlabeled F-actin solution via fluorescence microscopy. Whereas treadmilling and diffusive length fluctuations cannot account for the observed dynamics, our results suggest that at low salt condit ...[more]
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