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ABSTRACT: Objective
The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL).Study design
A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters.Results
The following results were found: (1) 184 STIC datasets; (2) with advancing gestation, ventricular volume, SV, CO, and adjusted CO increased, whereas EF decreased; (3) right ventricular (RV) volume was larger than the left ventricular (LV) volume in systole (0.50 vs 0.27 mL; P < .001) and diastole (1.20 vs 1.03 mL; P < .001); (4) there were no differences between the LV and RV in SV, CO, or adjusted CO; and (5) LV EF was greater than the RV EF (72.2 vs 62.4%; P < .001).Conclusion
Normal fetal cardiovascular physiology is characterized by a larger RV volume and a greater LV EF, resulting in similar LV and RV SV and CO.
SUBMITTER: Hamill N
PROVIDER: S-EPMC3175283 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Hamill Neil N Yeo Lami L Romero Roberto R Hassan Sonia S SS Myers Stephen A SA Mittal Pooja P Kusanovic Juan Pedro JP Balasubramaniam Mamtha M Chaiworapongsa Tinnakorn T Vaisbuch Edi E Espinoza Jimmy J Gotsch Francesca F Goncalves Luis F LF Lee Wesley W
American journal of obstetrics and gynecology 20110430 1
<h4>Objective</h4>The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL).<h4>Study design</h4>A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters.<h4>Results</h4>The fol ...[more]