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Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair.


ABSTRACT: In this issue of Genes & Development, Yang and colleagues (pp. 1847-1858) identify new components of a small ubiquitin-like modifier (SUMO)-like interaction network that orchestrates and fine-tunes the Fanconi anemia (FA) pathway and replication-coupled repair. This new pathway emphasizes the intricate interplay of ubiquitin (Ub) and SUMO networks in the DNA damage response.

SUBMITTER: van Wijk SJ 

PROVIDER: S-EPMC3175713 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair.

van Wijk Sjoerd J L SJ   Müller Stefan S   Dikic Ivan I  

Genes & development 20110901 17


In this issue of Genes & Development, Yang and colleagues (pp. 1847-1858) identify new components of a small ubiquitin-like modifier (SUMO)-like interaction network that orchestrates and fine-tunes the Fanconi anemia (FA) pathway and replication-coupled repair. This new pathway emphasizes the intricate interplay of ubiquitin (Ub) and SUMO networks in the DNA damage response. ...[more]

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