Ubiquitin and ubiquitin-like molecules in DNA double strand break repair.
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ABSTRACT:
SUBMITTER: Yu J
PROVIDER: S-EPMC7014694 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Ubiquitin and ubiquitin-like molecules in DNA double strand break repair.
Yu Jia J Qin Bo B Lou Zhenkun Z
Cell & bioscience 20200211
Both environmental and endogenous factors induce various forms of DNA damage. DNA double strand break (DSB) is the most deleterious DNA lesion. The swift initiation of a complexed network of interconnected pathways to repair the DNA lesion is essential for cell survival. In the past years, the roles of ubiquitin and ubiquitin-like proteins in DNA damage response and DNA repair has been explored. These findings help us better understand the complicated mechanism of DSB signaling pathways. ...[more]
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