Ontology highlight
ABSTRACT:
SUBMITTER: Fleming PA
PROVIDER: S-EPMC3176722 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Fleming Paul A PA Argraves W Scott WS Gentile Carmine C Neagu Adrian A Forgacs Gabor G Drake Christopher J CJ
Developmental dynamics : an official publication of the American Association of Anatomists 20100201 2
We evaluated the self-assembly properties of uniluminal vascular spheroids having outer layers of vascular smooth muscle cells and a contiguous inner layer of endothelial cells lining a central lumen. We showed that while pairs of uniluminal vascular spheroids suspended in culture medium fused to form a larger diameter spheroidal structure, spheroids in collagen hydrogels formed elongated structures. These findings highlight the potential use of uniluminal vascular spheroids as modules to engine ...[more]