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Random blood glucose measurement at antenatal booking to screen for overt diabetes in pregnancy: a retrospective study.


ABSTRACT:

Objective

To assess random venous blood glucose (RBG) measurement at antenatal booking to detect "overt diabetes in pregnancy" (ODIP).

Research design and methods

A retrospective analysis of regional hospital obstetric data from 2004-2008 was performed. Universal RBG screening was included at booking. Oral glucose tolerance test (OGTT) was administered if RBG >7.0 mmol/L or other indications, e.g., if a 50-g glucose challenge test was >7.7 mmol/L at 26-28 weeks. ODIP was based upon World Health Organization plasma glucose criteria for diabetes.

Results

RBG data were collected from 17,852/26,369 (67.7%) pregnancies around the initial antenatal visit; 3,007 women had an OGTT. The receiver operator curve area under the curve for RBG to detect ODIP was 0.86 (0.80-0.92) (assuming women without an OGTT did not have ODIP).

Conclusions

RBG at booking may provide a sufficiently sensitive screening tool for the detection of ODIP. We recommend further studies and comparison with fasting glucose and HbA(1c).

SUBMITTER: Church D 

PROVIDER: S-EPMC3177710 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Random blood glucose measurement at antenatal booking to screen for overt diabetes in pregnancy: a retrospective study.

Church David D   Halsall David D   Meek Claire C   Parker Richard A RA   Murphy Helen R HR   Simmons David D  

Diabetes care 20110815 10


<h4>Objective</h4>To assess random venous blood glucose (RBG) measurement at antenatal booking to detect "overt diabetes in pregnancy" (ODIP).<h4>Research design and methods</h4>A retrospective analysis of regional hospital obstetric data from 2004-2008 was performed. Universal RBG screening was included at booking. Oral glucose tolerance test (OGTT) was administered if RBG >7.0 mmol/L or other indications, e.g., if a 50-g glucose challenge test was >7.7 mmol/L at 26-28 weeks. ODIP was based upo  ...[more]

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