Ontology highlight
ABSTRACT:
SUBMITTER: Baudrimont A
PROVIDER: S-EPMC3177864 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Baudrimont Antoine A Penkner Alexandra A Woglar Alexander A Mamnun Yasmine M YM Hulek Margot M Struck Cathrin C Schnabel Ralf R Loidl Josef J Jantsch Verena V
PloS one 20110921 9
The cohesin complex is required for the cohesion of sister chromatids and for correct segregation during mitosis and meiosis. Crossover recombination, together with cohesion, is essential for the disjunction of homologous chromosomes during the first meiotic division. Cohesin has been implicated in facilitating recombinational repair of DNA lesions via the sister chromatid. Here, we made use of a new temperature-sensitive mutation in the Caenorhabditis elegans SMC-3 protein to study the role of ...[more]