Ontology highlight
ABSTRACT:
SUBMITTER: Faumont S
PROVIDER: S-EPMC3182168 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Faumont Serge S Rondeau Gary G Thiele Tod R TR Lawton Kristy J KJ McCormick Kathryn E KE Sottile Matthew M Griesbeck Oliver O Heckscher Ellie S ES Roberts William M WM Doe Chris Q CQ Lockery Shawn R SR
PloS one 20110928 9
Non-invasive recording in untethered animals is arguably the ultimate step in the analysis of neuronal function, but such recordings remain elusive. To address this problem, we devised a system that tracks neuron-sized fluorescent targets in real time. The system can be used to create virtual environments by optogenetic activation of sensory neurons, or to image activity in identified neurons at high magnification. By recording activity in neurons of freely moving C. elegans, we tested the long- ...[more]