Ontology highlight
ABSTRACT:
SUBMITTER: Dray N
PROVIDER: S-EPMC3182550 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Dray Nicolas N Tessmar-Raible Kristin K Le Gouar Martine M Vibert Laura L Christodoulou Foteini F Schipany Katharina K Guillou Aurélien A Zantke Juliane J Snyman Heidi H Béhague Julien J Vervoort Michel M Arendt Detlev D Balavoine Guillaume G
Science (New York, N.Y.) 20100701 5989
Annelids and arthropods share a similar segmented organization of the body whose evolutionary origin remains unclear. The Hedgehog signaling pathway, prominent in arthropod embryonic segment patterning, has not been shown to have a similar function outside arthropods. We show that the ligand Hedgehog, the receptor Patched, and the transcription factor Gli are all expressed in striped patterns before the morphological appearance of segments in the annelid Platynereis dumerilii. Treatments with sm ...[more]