Ontology highlight
ABSTRACT:
SUBMITTER: Lauri A
PROVIDER: S-EPMC4812194 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Lauri Antonella A Bertucci Paola P Arendt Detlev D
BioMed research international 20160316
In vertebrates, neurotrophic signaling plays an important role in neuronal development, neural circuit formation, and neuronal plasticity, but its evolutionary origin remains obscure. We found and validated nucleotide sequences encoding putative neurotrophic ligands (neurotrophin, NT) and receptors (Trk and p75) in two annelids, Platynereis dumerilii (Errantia) and Capitella teleta (Sedentaria, for which some sequences were found recently by Wilson, 2009). Predicted protein sequences and structu ...[more]