Ontology highlight
ABSTRACT:
SUBMITTER: Molina CL
PROVIDER: S-EPMC3192005 | biostudies-literature | 2007 Aug
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20070804 18
The type 2 intramolecular N-acylazo Diels-Alder reaction provides a regio- and stereoselective synthesis of bicyclic 1,2-diazine systems. A new method for the generation of N-acylazo dienophiles with tetra-n-butylammonium periodate is reported. X-ray crystallographic analysis allowed the quantification of structural distortions of the nonplanar bridgehead olefin and lactam functionalities in 1,2-diazine cycloadducts 11 and 15. Caprolactams and enantholactams were formed by stereoselective bridge ...[more]