Ontology highlight
ABSTRACT:
SUBMITTER: Wang CH
PROVIDER: S-EPMC3192790 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Wang Chiou-Huey CH Eng Hock-Liew HL Lin Kuei-Hsiang KH Chang Cheng-Hsien CH Hsieh Chi-An CA Lin Yen-Li YL Lin Tsun-Mei TM
PloS one 20111013 10
Toll-like receptors (TLRs) play pivotal roles in the innate immune system and control inflammatory responses and adaptive immunity. We previously evaluated associations between TLR7 and TLR8 gene SNPs and susceptibility to hepatitis C virus (HCV) infection. Our results suggested that TLR7IVS2-151G and TLR8-129G alleles were present at higher frequency in males of an HCV-infected group as compared to a control group (24.1% vs. 14.4%, p = 0.028; 17.6% vs. 6.8%, p = 0.004, respectively). Based upon ...[more]