Genetic variations in NF-?B were associated with the susceptibility to hepatitis C virus infection among Chinese high-risk population.
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ABSTRACT:
SUBMITTER: Tian T
PROVIDER: S-EPMC5758514 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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Genetic variations in NF-κB were associated with the susceptibility to hepatitis C virus infection among Chinese high-risk population.
Tian Ting T Wang Jie J Huang Peng P Li Jun J Yu Rongbin R Fan Haozhi H Xia Xueshan X Han Yaping Y Zhang Yun Y Yue Ming M
Scientific reports 20180108 1
Polymorphisms within NF-κB pathway genes may be linked to hepatitis C virus (HCV) infection susceptibility and outcomes. We investigated the associations between single nucleotide polymorphisms (SNPs) in NF-κB and the susceptibility as well as resolution of HCV infection. A Chinese population, including 1125 uninfected control cases, 558 cases with spontaneous viral clearance and 898 cases with persistent HCV infection, was genotyped for four SNPs (rs11820062, rs230530, rs1056890 and rs3774963) ...[more]
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